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The world needs an AIDS vaccine
More than 95% of all new infections are in developing countries, making HIV/AIDS among the most serious threats not only to global health, but to global development.
Prevention programs-including education, condom and clean needle distribution and peer counseling-have slowed the spread of HIV, but have not stopped it.
Treatment advances have yielded important new AIDS therapies, but the cost and complexity of their use put them out of reach for most people in the countries where they are needed the most. In industrialized nations where drugs are more readily available, side effects and increased rates of viral resistance have raised concerns about their long-term use.
Only an AIDS vaccine can end the HIV/AIDS pandemic.
We can end the AIDS for all time
The scientific consensus is that an AIDS vaccine is possible. Non-human primates have been protected by experimental AIDS vaccines. Some people repeatedly exposed to HIV resist infection and mount HIV specific immune responses, providing important clues for the design of an effective AIDS vaccine. Other infectious diseases have been controlled by vaccines. Smallpox was eradicated in 1977 because of an effective vaccine. Polio has been eliminated from all but six countries in the world. Measles and yellow fever have been controlled by vaccines.
The prospects for success have never been greater.
Advances in molecular biology and basic HIV research have led to the development of promising strategies for effective AIDS vaccines.
Imagine a World without AIDS.
No single organization or government can end the AIDS epidemic. Just as no country, no region, and no community is immune to HIV, all must play a role in the effort to bring the epidemic under control. With greater commitment from a range of governments, foundations, scientists and committed individuals the world will at last have a realistic chance of creating a vaccine to end AIDS for all time.
IAVI and its partners are committed to speeding the discovery and distribution of a safe, effective and accessible AIDS vaccine. Developing an AIDS vaccine to save lives and economies will be one of the world's greatest achievements. Not to do so would be one of its greatest failures.
For more information about the global AIDS pandemic visit the UNAIDS website, and IAVI website.
Annual check-ups
Long-term prospects
Both types of diabetes have the risk of complications.
Acute complications
Late-stage diabetic complications
Late-stage complications do not usually develop for 10-15 years with Type 1 diabetes.
In Type 2 diabetes, however, symptoms can appear close to the time of actual diagnosis because the disease may go undetected for longer.
Many studies now show that good glucose control can significantly reduce or even stop complications. This means keeping the blood sugar level as close to normal as possible.
Recent studies have also confirmed the need for people with diabetes to reduce their risk of atherosclerosis (fatty deposits in your arteries).
This is because if you have Type 2 diabetes, you have a four to five times greater risk of developing serious problems with your circulation that can lead to a heart attack or a stroke.
The main factors that increase your risk are:
By taking measures to address these issues, you will reduce your chance of developing complications such as heart disease.
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Insulin injections increase the amount of insulin in your body and bring down the blood sugar level. Insulin injections are used in Type 1 diabetes and in some cases of Type 2.
There are different types of oral medication for treating Type 2 diabetes:
Treatment for diabetes depends on the individual.
It starts the first time you give yourself an insulin injection or take a diabetes tablet, and continues through eating a well-balanced diet and starting an exercise programme.
To help you get the most out of treatment, consult your GP or hospital healthcare team, which should include a diabetes nurse specialist.
Blood sugar levels
Monitoring blood sugar levels is an important aspect of treatment, especially in Type 1 diabetes where levels can change markedly.
This can be done easily at home with a small blood glucose meter.
Depending on the reading, you may need to adjust your diet, the amount you exercise or your insulin intake.
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There are also other types of diabetes.
How common is diabetes?
In the UK around 1.6 million people have been diagnosed with diabetes.
But Type 2 diabetes often has few symptoms in the early stages - it's estimated that half of those with Type 2 diabetes have not yet been diagnosed.
The last 30 years has seen a threefold increase in the number of cases of childhood diabetes.
Obesity levels have also risen - and this has led to Type 2 diabetes, which is linked to diet, being seen for the first time in young people in Europe and America.
But obesity doesn't explain the increase in the numbers of Type 1 diabetes in children - who make up the majority of new cases.
What causes diabetes?
Insulin is a hormone produced by the pancreas gland in the abdomen. It controls the use of glucose within the body.
The blood sugar level will rise if:
It's thought Type 2 diabetes is related to factors associated with a Western lifestyle, since it's most common in people who are overweight and who don't get enough exercise.
Gestational diabetes is brought about by the many hormone changes and demands placed upon the body during pregnancy.
Secondary diabetes is much like Type 2 diabetes. It's quite variable, depending on the underlying cause.
Common symptoms of diabetes
Glucose is one of the body’s main fuels. If there isn't enough, blood sugar levels rise and glucose is secreted into urine. This causes:
People with Type 1 diabetes usually develop these symptoms within days or weeks.
In Type 2 diabetes, these symptoms often don't show for years. Many are diagnosed by chance through routine medical check-ups.
Heredity plays a part in diabetes, but only 10 per cent of people with Type 1 have a family history of diabetes. For Type 2, this rises to 30 per cent.